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Comparative analysis of
composition, side effects, dosage and habit formation of commonly drugs
prescribed for AD/HD
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Drug |
Side Effects |
Dosage |
Habit Forming |
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C. Name:
Ritalin
Group:
Methylphenidate
Mnfcr:
Novartis Pharmaceutical Corp
Other Brand Names:
Concerta, Metadate Methylphenidate Hcl, Rilatine, Ritalin-SR,
Rubifen
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Long term effect on child:
May cause slower growth (height and weight) in children
Common side effects:
Nervousness, difficulty falling asleep or staying asleep, dizziness,
upset stomach, vomiting, loss of appetite, stomach pain, diarrhea,
headache, couth, runny nose, and other cold symptoms. Depression,
chronic abuse can lead to tolerance and psychic dependency with
varying degrees of abnormal behavior. Frank psychotic episodes can
occur. Patients with agitation may react adversely.
CBC and platelet count (lab work) are
advised.
Cardiac
side effects: Necrotizing
vasculitis, thrombocytopenia purpura, blood pressure and pulse
changes, rapid heart beat, cardiac arrhythmia, angina.
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All forms taken by mouth. Usually
taken 2-3 times a day. Extended release tablets taken once a day in
the morning.
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Can be on a psychological level
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C. Name:
AD/HDerall
Group:
Amphetamine (Laevoamphetamine
(Benzedrine)
and Methamphetamine (Methedrine)
are collectively referred to as Amphetamines.)
Mnfcr:
Other Brand Names
AD/HDerall XR, Desoxyn, Dexedrine, DextroStat
Desipramine, Desipramine HCL,
Pertofrane, Amphaetex, Das, Dexampex, Desamphetamine, Dexamphetamini
Sulfas, Dexedrina, Dexedrine Spansule, Dextrostat, Ferndex, Oxydess,
Spancap
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Long term effect on child:
Used for long periods of time in children may cause unwanted effects
on behavior and growth. May cause slower growth (height and weight) in
children
Common
side effects: Nervousness,
restlessness, difficulty falling or staying asleep, mood swings,
agitation, dizziness, tiredness, weakness, shaking hands that you
cannot control, headache, changes in sex drive or ability, dry mouth,
stomach pain, upset stomach, vomiting, diarrhea, constipation, loss of
appetite, weight loss, bad taste in mouth. Amphetamine with high
potential for abuse, controlled substance, may lead to drug
dependence, may exacerbate behavior disturbances and thought
disorders, and psychotic episodes.
Cardiac side effects:
palpitations, rapid heartbeat, hypertension, and cardiomyopathy with
chronic use of amphetamines.
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Tablet usually taken 2-3 times daily.
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Can be on a psychological level
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C. Name:
Strattera
Group:
Atomoxetine
Mnfcr:
Lilly
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Long-term effect on child:
No long-term side effects known as of date.
Common side effects:
Heartburn, upset stomach, vomiting, loss of appetite, constipation,
dry mouth, excessive tiredness, difficulty falling asleep or staying
asleep, dizziness, headache, mood swings, irritability, weight loss,
decreased sex drive or ability, difficulty urinating, painful
menstrual periods, cough, runny nose, violent behavior.
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Capsule to be taken by mouth.
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No
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Comparative analysis of
composition, side effects, dosage and habit formation of drugs NOT
commonly prescribed for AD/HD
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Drug |
Side Effects |
Dosage |
Habit Forming |
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C. Name:
Wellbutrin,
Wellbutrin SR
Group:
Bupropion hydrochloride
Mnfcr:
Glaxosmithclime
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Children and teenagers
who take (mood elevators) such as Wellbutrin are more likely to think
about harming or killing themselves. The safety and effectiveness in
children under 18 years old have not been established. Although they
are more sensitive to antidepressant drugs, older people have
responded no differently to Wellbutrin than younger people
Common side effects:
Drowsiness, restlessness, excitement, anxiety, dry mouth, difficulty
falling asleep or staying asleep, dizziness, headache, upset stomach,
vomiting, tremor, weight loss, constipation, excessive sweating,
agitation, anxiety, restlessness, delusions, hallucinations, psychotic
episodes, paranoia, mania, seizures, hostility, depression,
depersonalization, mood instability, thought disorder, suicidal
ideation. Weight gain and weight loss.
May take 4 weeks or
longer to feel the full benefit
Cardiac
side effects:
edema, chest pain, EKG abnormalities, shortness of breath, heart
attack.
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Either a
sustained-release or extended-release tablet taken by mouth.
Wellbutrin: 3 equal doses
spaced evenly throughout the day. At least 6 hours between doses.
Wellbutrin SR: 2 doses,
at least 8 hours apart.
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Can be on a psychological level
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C. Name:
Paxil
Group:
Selective Serotonin Reuptake Inhibitors
(SSRI)) Paroxetine hydrochloride
Mnfcr:
Glaxosmithclime
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Common side effects:
Anxiety, restlessness, mania/hypomania, seizures, suicide, impaired
judgment, agitation, amnesia, emotional lability, apathy,
depersonalization, hallucinations, hostility, paranoid reaction,
personality disorder, delusions, aggressive reactions, neurosis,
antisocial reaction, delirium, drug dependence, stupor and phobia.
Cardiac
side effects: hemorrhage,
hypertension, angina, arrhythmias, congestive heart failure, heart
attack, rapid heart beat, chest pain, atrial fibrillation, cerebral
embolism, heart block, dizziness, syncope, fluid retention, EKG
abnormalities
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Paxil: Once a day, in either the
morning or the evening.
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Can be on a psychological level
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C. Name:
Prozac
Group:
Selective Serotonin Reuptake Inhibitors
(SSRI)) Fluoxetine hydrochloride
Mnfcr:
Lilly
Other Brand Names:
Adofen, Deproxin, Fluctin, Fluctine,
Fludac, Flufran, Flunil, Fluoxac, Fluoxeren, Fluoxil, Fluoxeron,
Flutine, Fluxil, Fontex, Lovan, Margrilan, Oxetine, Prodep, Prozac 20,
Rowexetina.
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Common side effects:
Anxiety, restlessness, mania/hypomania, seizures, suicide, impaired
judgment, agitation, amnesia, emotional liability, apathy,
depersonalization, hallucinations, hostility, paranoid reaction,
personality disorder, delusions, aggressive reactions, neurosis,
antisocial reaction, delirium, drug dependence, stupor and phobia.
Cardiac
side effects: hemorrhage,
hypertension, angina, arrhythmias, congestive heart failure, heart
attack, rapid heart beat, chest pain, atrial fibrillation, cerebral
embolism, heart block, dizziness, syncope, fluid retention, EKG
abnormalities.
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Prozac usually is taken
once or twice a day. |
Can be on a psychological level
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C. Name:
Zoloft
Group:
Selective Serotonin Reuptake Inhibitors
(SSRI)) Sertraline
Mnfcr:
Pfizer Inc |
Common side effects:
Anxiety, restlessness, mania/hypomania, seizures, suicide, impaired
judgment, agitation, amnesia, emotional liability, apathy,
depersonalization, hallucinations, hostility, paranoid reaction,
personality disorder, delusions, aggressive reactions, neurosis,
antisocial reaction, delirium, drug dependence, stupor and phobia.
Cardiac
side effects: hemorrhage,
hypertension, angina, arrhythmias, congestive heart failure, heart
attack, rapid heart beat, chest pain, atrial fibrillation, cerebral
embolism, heart block, dizziness, syncope, fluid retention, EKG
abnormalities.
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Zoloft is taken once a
day, in either the morning or the evening. |
Can be on a psychological level
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C. Name:
Luvox
Group:
Selective Serotonin Reuptake Inhibitors
(SSRI) Fluvoxamine maleate
Mnfcr:
LUVOX Solvay Pharma
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Common side effects:
Anxiety, restlessness, mania/hypomania, seizures, suicide, impaired
judgment, agitation, amnesia, emotional liability, apathy,
depersonalization, hallucinations, hostility, paranoid reaction,
personality disorder, delusions, aggressive reactions, neurosis,
antisocial reaction, delirium, drug dependence, stupor and phobia.
Cardiac side effects:
hemorrhage, hypertension, angina, arrhythmias, congestive heart
failure, heart attack, rapid heart beat, chest pain, atrial
fibrillation, cerebral embolism, heart block, dizziness, syncope,
fluid retention, EKG abnormalities.
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Luvox may be taken with or without food
as directed by the doc.
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Can be on a psychological level
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C. Name:
Catapres
Group:
Clonidine
Mnfcr:
Boehringer Ingelheim
Other Brands:
Arkamin, Barclyd, Capril,
Caprysin, Catapres-TTS, Catapresan, atapresan 100, Catapresan Depot,
Catapressan, Clonidine, Daipres, Dixarit, Haemiton, Normopresan,
Paracefan, Sulmidine, Taitecin.
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Common side effects:
Adult high blood pressure drug: delirium, mental depression, visual
and auditory hallucinations, restlessness, anxiety, agitation,
irritability, other behavioral changes, drowsiness.
Cardiac side-effects: congestive
heart failure, cerebrovascular accident (stroke), EKG abnormalities,
arrhythmias, chest pain, syncope, high blood pressure, rapid heartbeat
and palpitations.
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The usual starting dose
is 0.1 milligram, twice a day (usually in the morning and at bedtime).
The most common effective dosages range
from 0.2 milligram to 0.6 milligram per day divided into smaller
doses. The maximum effective dose is 2.4 milligrams per day; however,
this dose is not usually prescribed.
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Can be on a psychological level
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C. Name:
Norpramin / Pertofrane (generic name
desipramine)
Group:
Clonidine hydrochloride
Mnfcr:
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Common side effects:
Psychiatric disturbances, seizures, anxiety, hallucinations,
restlessness, agitation, nightmares, insomnia, confusion, tremors.
Cardiac side effects: Sudden death in children, heart attack,
heart block, stroke, arrhythmias, rapid heart rate.
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Oral medication starts with 25 mg 2 to
4 times daily. Increases by 25 mg daily in intervals of one week.
Maintenance is 100 to 200 mg in 24 hours.
Maximum limit of dosage is 300 mg in 24 hours.
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Can be on a psychological level
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C.Name:
Tofranil
Group:
(Imipramine)
Brand Names
Antidep, Apo-Imipramine, Chrytemin, Daypress, Depsol, Depsonil,
Ethipramine, Fronil, Imavate, Imidol, Imimine, Imine, Imipramin,
Imipramine Hcl, Imiprex, Imiprin, Impril, Janimine, Medipramine,
Melipramine, Mipralin, Norfranil, Novopramine, Presamine, Primonil,
Pryleugan, Sermonil, Sipramine, Surplix, Talpramin, Tipramine, Tofril,
Tofranil-PM, Venefon. |
Common side effects:
Abdominal cramps, anxiety, black tongue, bleeding sores, blood
disorders, blurred vision, breast development in males, confusion,
congestive heart failure, constipation or diarrhea, cough, fever, sore
throat, delusions, dilated pupils, disorientation, dizziness,
drowsiness, dry mouth, episodes of elation or irritability, excessive
or spontaneous flow of milk, fatigue, fever, flushing, frequent
urination or difficulty or delay in urinating, hair loss,
hallucinations, headache, heart attack, heart failure, high blood
pressure, high or low blood sugar, high pressure of fluid in the eyes,
hives, impotence, increased or decreased sex drive, inflammation of
the mouth, insomnia, intestinal blockage, irregular heartbeat, lack of
coordination, light-headedness, loss of appetite, nausea, nightmares,
odd taste in mouth, palpitations, purple or reddish-brown spots on
skin, rapid heartbeat, restlessness, ringing in the ears, seizures,
sensitivity to light, skin itching and rash, stomach upset, stroke,
sweating, swelling due to fluid retention (especially in face or
tongue), swelling of breasts, swelling of testicles, swollen glands,
tendency to fall, tingling, pins and needles, and numbness in hands
and feet, tremors, visual problems, vomiting, weakness, weight gain or
loss, yellowed skin and whites of eyes.
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The usual starting dose is 75
milligrams a day. The doctor may increase this to 150 milligrams a
day. The maximum daily dose is 200 milligrams.
Tofranil is not to be used in children
to treat any condition but bedwetting, and its use will be limited to
short-term therapy. Safety and effectiveness in children under the age
of 6 have not been established. Total daily dosages for children
should not exceed 2.5 milligrams for each 2.2 pounds of the child's
weight.
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Can be on a psychological level
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C.Name:
Buspar
Group:
Buspirone hydrochloride
Mnfcr:
Other Brand Names:
Ansial, Ansiced, Ansitec, Anxinil,
Anxiolan, Barpil, Bespar, Biron, Busirone, Buspar, Buspirone,
Kallmiren, Narol, Nerbet, eurosine, Normaton, Paxon, Relac, Sburol,
Tutran |
Common side effects:
Dizziness, dry mouth, fatigue, headache, light-headedness, nausea,
nervousness, unusual excitement Less common or rare side effects may
include:
Anger/hostility, blurred vision, bone aches/pain, confusion,
constipation, decreased concentration, depression, diarrhea, fast,
fluttery heartbeat, incoordination, muscle pain/aches, numbness, pain
or weakness in hands or feet, rapid heartbeat, rash, restlessness,
stomach and abdominal upset, sweating/clamminess, tingling or pins and
needles, tremor, urinary incontinence, vomiting, weakness.
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The recommended starting dose is a
total of 15 milligrams per day divided into smaller doses, usually 5
milligrams 3 times a day. Every 2 to 3 days, your doctor may increase
the dosage 5 milligrams per day as needed. The daily dose should not
exceed 60 milligrams.
The safety and effectiveness of Buspar
have not been established in children less than 18 years of age.
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Can be on a psychological level
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C. Name:
Cylert
Group:
Pemoline
Mnfcr:
Pfizer Inc
Other Brand Names:
Betanamin, Cylert, Tradon.
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Common side effects:
Insomnia, Depression, dizziness, drowsiness, hallucinations, headache,
hepatitis and other liver problems, increased irritability,
involuntary, fragmented movements of the face, eyes, lips, tongue,
arms, and legs, loss of appetite, mild depression, nausea, seizures,
skin rash, stomachache, suppressed growth, uncontrolled vocal
outbursts (such as grunts, shouts, and obscene language), weight loss,
yellowing of skin or eyes.
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The recommended beginning dose is 37.5
milligrams daily. Dosages may be gradually increased if needed. Most
children take doses ranging from 56.25 to 75 milligrams a day. The
maximum recommended daily dose of Cylert is 112.5 milligrams.
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Can be on a psychological level
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Source: Drug
information obtained from
http://www.nlm.nih.gov/medlineplus - a service of the US National
Library of Medicine. And
www.healthsquare.com
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