The Course Of Oppositional Defiant Disorder In Children With ADHD

As discussed in several studies previously reviewed in ADHD RESEARCH UPDATE, the development of significant behavioral problems in children with ADHD is often associated with more negative long-term outcomes. For this reason, understanding the factors associated with both the development and persistence of important conduct problems in children with ADHD is extremely important.

This issue was the focus of an interesting study published in a recent issue of the Journal of the American Academy of Child and Adolescent Psychiatry (August, G.J., Realmuto, G.M., Joyce, T. & Hektner, J.M. (1999). Persistence and desistance of Oppositional Defiant Disorder in a community sample of children with ADHD. (JAACP, 38, 1262-1270). In this study, the authors began with a sample of over 7000 children attending 22 different elementary schools in a suburban community, and using a combination of behavioral screening procedures and diagnostic interviews, identified those children who met diagnostic criteria for ADHD alone, ADHD and Oppositional Defiant Disorder (ODD), and neither diagnosis.

As you may recall from a prior issue of ADHD RESEARCH UPDATE, the essential feature of ODD is a persistent pattern of negativistic, defiant, disobedient, and hostile behavior towards authority figures that persists for at least 6 months. Children with ODD often lose their temper, argue with adults, actively defy and refuse to comply with rules and other demands, deliberately annoy others, appear angry and resentful, act spiteful, and blame others for their mistakes and misbehavior. Although all children may display such behaviors from time to time, in children with ODD these behaviors occur much more often and with greater intensity.

In this study, the authors were interested in learning several things. First, they wanted to study what background factors differed between children with ADHD alone, from those who were diagnosed with ADHD and ODD. Second, they were interested in identifying factors predicted the persistence of ADHD and ODD. Finally, they wondered how often ODD escalated into Conduct Disorder (CD) and what factors were associated with this progression. As you may recall, CD is an even more serious behavioral disturbance than ODD that often involves criminal type behavior (for a more thorough discussion of ODD and CD go to http://www.helpforadd.com/oddcd.html.

The sample of children identified to study included 79 with ADHD alone, 43 with ADHD and ODD, and 111 children with neither diagnosis who were included as a comparison group. Children were approximately 9 year olds at the start of the study and were from primarily middle-class backgrounds. The ratio of boys to girls in the sample was about 4:1. This study was conducted in Minnesota, and 95% of the sample were white.

At the initial assessment, several measures were collected in addition to the diagnostic interview data that was obtained for all participants. These additional measures included basic demographic information on the families (e.g. socioeconomic status, single parent status vs. intact family), psychiatric information on parents (i.e. whether parents had a history of any psychiatric diagnosis), and parenting practices. This latter factor was designed to evaluate parents' use of different disciplinary practices and the authors were especially interested in the use of what they considered to be "negative practices" that involved inconsistent and punitive approaches to managing children's behavior.

Four years after this initial assessment, a second diagnostic evaluation was conducted, in which the authors were able to reevaluate approximately 60% of the original sample. Although it would have been preferable if they were able to retain a larger portion of the original sample, analyses they conducted indicated that participants who dropped out did not differ significantly on most characteristics from those who were reevaluated. Thus, it is reasonable to assume that their findings are not unduly influenced by their having a
non-representative sample for the follow-up assessment.

Using this second round of diagnostic data, they were able to look at changes in the symptom picture for each child, changes in the overall rate of diagnosis, and to examine what types of background factors were associated with these changes. The major questions addressed and the results of their analyses are summarized below.

What was the stability of the initial diagnoses?

Of the 79 children who were diagnosed with ADHD alone at the initial evaluation and reevaluated 4 years later, 36 - about 46% - continued to meet diagnostic criteria for ADHD and no additional diagnosis. Another 21 - about 27% - continued to meet diagnostic criteria for ADHD and were also now diagnosed with ODD as well. The same number - 21 - no longer met ADHD diagnostic criteria and received no diagnosis at the follow up.

This is certainly encouraging in that it indicates that a significant number of children with ADHD do experience a diminishing of symptoms over time to the point where they no longer qualify for the diagnosis. It is important to be aware, however, that even though a child/teen may no longer meet full diagnostic criteria, he or she will often still be adversely affected by residual symptoms of ADHD and continue to need extra help and support. Not meeting full diagnostic criteria is definitely not always the same as not having any difficulties related to ADHD symptoms.

Of the 43 children initially diagnosed with both ADHD and ODD, almost 50% retained these original diagnoses. Fifteen still met diagnostic criteria for ADHD, but their behavioral symptoms had improved to where they were no longer diagnosed with ODD. Only 4 children from this group - about 10% - were not given either diagnosis at follow up.

What factors predicted the emergence and persistence of ODD?

The authors first examined the factors associated with an ODD diagnosis at the initial assessment. Specifically, their analyses considered whether child IQ, socioeconomic status, history of psychiatric difficulty in the child's family, gender, and negative parenting practices increased the likelihood of the child being diagnosed with ODD.

The results indicated that only negative parenting practices was a significant predictor that a child with ADHD would also be diagnosed with ODD. To put this in perspective, they found that children whose parents scored in the top 15% of the sample on a measure of negative parenting practices were about twice as likely as other children to be diagnosed with ODD. Children from families of lower socioeconomic status were somewhat more likely to be diagnosed with ODD.

At the follow up evaluation, the strongest predictor of an ODD diagnosis was whether or not the child had ODD at the initial assessment. Such children were 8 times more likely than others to be diagnosed with ODD at the second evaluation. In addition, however, negative parenting practices was also an important predictor of whether or not the ODD diagnosis would persist. Thus, children with ODD at time 1 whose parents were in the top 15% for the negative parenting practices measure were almost twice as likely as other to still have ODD 4 years later.

In addition, children diagnosed with ADHD initially also tended to be more likely to be diagnosed with ODD 4 years later than the 111 comparison children who had no diagnosis at time 1. Thus, this is an indication that the presence of ADHD increases the likelihood that a child will develop important behavior problems as well.

It is important to note that although these data indicate that parenting practices are associated with the emergence and persistence of ODD, they do not necessarily mean that negative parenting practices were the initial "cause" of the child's ODD. Remember, all of these children were also diagnosed with ADHD and children with ADHD present unique challenges to parents in terms of behavior management issues.

Sometimes, the stresses that occur between parents and children in response to a child's ADHD symptoms can precipitate a pattern of negative exchanges that do contribute to the development of important behavior problems. Thus, negative parenting practices can emerge in response to the frustration associated with parenting a child with ADHD, which is certainly different from arguing that such practices are the original cause of a child's oppositional and defiant behavior.

It should also be noted that children with persistent ODD were more likely than children whose ODD "desisted" to have extreme problems with temper at the initial evaluation along with a tendency to be spiteful. Thus, these particular symptoms appear to be especially common in children who are likely to show persistent behavior problems.

What factors were associated with an initial diagnosis of ADHD or the persistence of ADHD?

These results provide an interesting contrast to the results discussed above for ODD. At the initial evaluation, none of the family background factors - e.g. socioeconomic status, single parent vs. intact family etc. - was associated with whether a child had ADHD, nor was the negative parenting practices variable. Compared to parents of children without ADHD, however, parents of children with ADHD were more likely to have ADHD themselves, either currently or at an earlier time in their lives.

In addition, the only significant predictor of whether a child was diagnosed with ADHD at follow-up was whether he or she was given the diagnosis originally. Thus, parenting practices did not seem to be related to whether a child was diagnosed with ADHD initially, or whether the child developed ADHD over the subsequent 4 years.


IMPLICATIONS

I think there are several important implications that emerge from this study. First, the fact that almost 75% of children diagnosed with ADHD initially were still diagnosed with ADHD 4 years later indicates both that:

1. The disorder tends to be relatively stable over time, but

2. For a significant percentage of children, symptoms diminish over time to a point that the diagnosis no longer applies.

At this point, it is still not possible to accurately predict which of these possibilities will be true for a particular child. It is also important to note that even among children who no longer meet full diagnostic criteria for ADHD, in many instances they can continue to struggle with symptoms of the condition. Thus, no longer meeting full diagnostic criteria is not the same thing as a complete remission from the difficulty that ADHD can cause.

The reason I think this point is so important is because I have seen some teens and their parents who were confused by the fact that they had been told the teen no longer "had ADHD" and yet it was clear that the adolescent was continuing to struggle in significant ways. Even when the full diagnosis no longer applies, therefore, it can be critically important to continue to provide the structure, assistance, and support that is often needed.

The findings pertaining to the emergence and persistence of ODD are also quite interesting. Recall that the primary predictor of ODD was the degree of negative parenting practices that parents engaged in. These would include such practices as overly harsh and punitive discipline, inconsistent enforcement of limits and rules, overly restrictive rules, unrealistic behavioral expectations, and failing to reward appropriate behavior.

As discussed above, these findings should not be interpreted as proving that parenting is the fundamental cause of ODD. What these data do clearly suggest, however, is that this is an area where parents have the potential to have a substantial and important impact on their child's development. From this study alone, we do not know what the long-term outcomes for children with persistent ODD will be. Although few such children developed Conduct Disorder - a more serious behavioral disturbance - during the course of the study, it is certainly reasonable to speculate that the outcomes for those with persistent ODD are likely to be more problematic.

The fact that such persistent behavior problems are associated with a higher degree of negative parenting practices clearly implies that altering such practices can play a critical role in promoting better behavioral adjustment in one's child. Thus, getting professional assistance in learning the types of child management strategies that can help to accomplish this can be an enormously useful step for parents to take. I've got an introduction to behavioral interventions at http://www.helpforadd.com/behtreat.html and would also recommend a book called "Your Defiant Child" by Dr. Russell Barkley. These resources can help get you started, but if this is a real concern of yours, then consultation with an experienced child mental health professional in your area would be highly recommended.


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